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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-26775

Ferlazzo, G; Münz, C (2009). Dendritic cell interactions with NK cells from different tissues. Journal of Clinical Immunology, 29(3):265-273.

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INTRODUCTION: In recent years, it has been realized that innate lymphocytes do not act in isolation but potentiate their efficiency by interacting with each other, resulting even in the regulation of adaptive immune response. One such cross-talk exists between dendritic cells (DCs) and natural killer (NK) cells. Here, we summarize recent studies on which subsets of these two innate immune components participate in this interaction, how it influences immune responses, and to which extent similar stimuli are integrated by DCs and NK cells during innate immunity. CONCLUSION: We suggest that this cross-talk should be harnessed by activating both of these innate leucocyte populations with new adjuvant formulations for immunotherapies.

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of Experimental Immunology
DDC:570 Life sciences; biology
610 Medicine & health
Deposited On:06 Jan 2010 13:36
Last Modified:27 Nov 2013 17:25
Publisher DOI:10.1007/s10875-009-9283-y
PubMed ID:19280325
Citations:Web of Science®. Times Cited: 32
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Scopus®. Citation Count: 29

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