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Post-processing technique for improved assessment of hard tissues in the submicrometer domain using local synchrotron radiation-based computed tomography


Schneider, P; Voide, R; Stampanoni, M; Müller, R (2009). Post-processing technique for improved assessment of hard tissues in the submicrometer domain using local synchrotron radiation-based computed tomography. Biomedizinische Technik. Biomedical Engineering, 54(1):48-54.

Abstract

During the last two decades micro-computed tomography has become the method of choice for the non-destructive assessment and quantitative morphometry of hard tissues in three dimensions. With the advent of third-generation synchrotron radiation sources, micro-computed tomography in the micrometer range has become feasible and has been employed to analyze local bone tissue properties. However, owing to limitations regarding the tradeoff between object size and spatial resolution, non-destructive conventional global computed tomography of hard tissues, such as bone, remains unachievable in the submicrometer domain so far. Here, we report on a post-processing technique for the assessment of hard tissues using local synchrotron radiation-based computed tomography, which overcomes this experimental limitation.

During the last two decades micro-computed tomography has become the method of choice for the non-destructive assessment and quantitative morphometry of hard tissues in three dimensions. With the advent of third-generation synchrotron radiation sources, micro-computed tomography in the micrometer range has become feasible and has been employed to analyze local bone tissue properties. However, owing to limitations regarding the tradeoff between object size and spatial resolution, non-destructive conventional global computed tomography of hard tissues, such as bone, remains unachievable in the submicrometer domain so far. Here, we report on a post-processing technique for the assessment of hard tissues using local synchrotron radiation-based computed tomography, which overcomes this experimental limitation.

Citations

7 citations in Web of Science®
9 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Biomedical Engineering
Dewey Decimal Classification:170 Ethics
610 Medicine & health
Date:2009
Deposited On:03 Feb 2010 14:14
Last Modified:05 Apr 2016 13:43
Publisher:De Gruyter
ISSN:0013-5585
Publisher DOI:10.1515/BMT.2009.007
PubMed ID:19182873

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