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Sanders, R D; Schuepbach, D; Goldstein, G; Haas, G L; Sweeney, J A; Keshavan, M S (2004). Relationships between cognitive and neurological performance in neuroleptic-naïve psychosis. Journal of Neuropsychiatry and Clinical Neurosciences, 16(4):480-487.

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The authors explored relationships between neuropsychological performance and neurological exam abnormalities in 86 never-medicated patients with nonorganic psychosis (59 with schizophrenia or schizoaffective disorder) and 51 healthy subjects. Assessments include a reliable subset of the Neurological Evaluation Scale (rNES) and several neuropsychological tests of attention, executive function, memory, and current and premorbid intelligence. Principal components analysis of the rNES yielded two main factors. Of these, CogPer (consisting of more cognitively demanding perceptual tasks) showed stronger relationships than RepMot (consisting of repetitive manual motor tasks) to neuropsychological measures. Customarily, frontal neuropsychological tasks also relate more strongly to CogPer than to RepMot. Approximately one-half of the variability in these cognitive and neurological assessments is shared.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Psychiatric University Hospital Zurich > Clinic for Psychiatry, Psychotherapy, and Psychosomatics
DDC:610 Medicine & health
Deposited On:26 Jan 2010 08:17
Last Modified:27 Nov 2013 16:21
Publisher:American Psychiatric Press
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:10.1176/appi.neuropsych.16.4.480
PubMed ID:15616175
Citations:Web of Science®. Times Cited: 14
Google Scholar™
Scopus®. Citation Count: 18

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