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Rickenbacher, A; Breitenstein, S; Lesurtel, M; Frilling, A (2009). Efficacy of TachoSil a fibrin-based haemostat in different fields of surgery - a systematic review. Expert Opinion on Biological Therapy, 9(7):897-907.

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BACKGROUND: Proper haemostasis is an important prerequisite for a successful outcome in all operative fields. TachoSil is used in many surgical specialties, especially for diffuse bleeding. However, TachoSil is not only used for haemostasis but also for closure of other anatomical structures. OBJECTIVE: To review the literature concerning the efficacy of TachoSil, a topical fibrin-based haemostat. METHODS: PubMed was searched for data on TachoSil and TachoComb from clinical trials and basic research. RESULTS/CONCLUSION: TachoSil is used in many surgical specialties and has proven to be a valuable tool for several indications. It also seems to be cost effective. Solid data from randomized controlled trials are available for liver surgery, thoracic surgery and urology where a positive value is clearly documented.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Visceral and Transplantation Surgery
DDC:610 Medicine & health
Deposited On:30 Jan 2010 18:38
Last Modified:27 Nov 2013 21:59
Publisher:Informa Healthcare
Publisher DOI:10.1517/14712590903029172
PubMed ID:19527109
Citations:Web of Science®. Times Cited: 20
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Scopus®. Citation Count: 25

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