Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-28786
Notarangelo, L D; Fischer, A; Geha, R S; Casanova, J-L; Chapel, H; Conley, M E; Cunningham-Rundles, C; Etzioni, A; Hammartröm, L; Nonoyama, S; Ochs, H D; Puck, J; Roifman, C; Seger, R; Wedgwood, J (2009). Primary immunodeficiencies: 2009 update. Journal of Allergy and Clinical Immunology, 124(6):1161-1178.
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More than 50 years after Ogdeon Bruton's discovery of congenital agammaglobulinemia, human primary immunodeficiencies (PIDs) continue to unravel novel molecular and cellular mechanisms that govern development and function of the human immune system. This report provides the updated classification of PIDs that has been compiled by the International Union of Immunological Societies Expert Committee on Primary Immunodeficiencies after its biannual meeting in Dublin, Ireland, in June 2009. Since the appearance of the last classification in 2007, novel forms of PID have been discovered, and additional pathophysiology mechanisms that account for PID in human beings have been unraveled. Careful analysis and prompt recognition of these disorders is essential to prompt effective forms of treatment and thus to improve survival and quality of life in patients affected with PIDs.
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|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic|
|DDC:||610 Medicine & health|
|Deposited On:||11 Mar 2010 15:25|
|Last Modified:||28 Nov 2013 01:06|
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