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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-29015

Davidov, Eldad; Breitscheidel, L; Clouth, J; Reips, M; Happich, M (2009). Diabetic retinopathy and health-related quality of life. Graefe's Archive for Clinical and Experimental Ophthalmology, 247(2):267-272.

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To describe the impact of co-morbidities, visual acuity, diabetic retinopathy (DR) grade, and macular edema (ME) on the health-related quality of life (HRQOL) among patients with diabetic retinopathy.

Analysis of data of 207 patients with diabetic retinopathy from Germany in 2003. HRQOL assessment was done using the generic (SF-12) questionnaire. It was hypothesized that exogenous variables (co-morbidities, visual acuity impairment, DR, and ME) would have an impact on HRQOL. Using a structural equation modelling procedure, the effects of exogenous variables on endogenous variables physical component summaries (PSC) and mental component summaries (MCS) reflecting HRQOL were tested.

The number of co-morbidities had a negative effect on visual acuity (b = −0.26, standardized) and a similar negative effect on PCS (b = −0.27). DR grade had a negative effect on visual acuity (b = −0.19) and a positive effect on the variable ME (b = 0.44). ME displayed a negative effect on visual acuity (b = −0.58) and also on MCS (b = −0.29). Visual acuity had a positive effect (b = 0.48) on PCS.

Presence of DR and ME, visual acuity impairment and patient co-morbidities lead to significant impairment of both the physical and mental components of HRQOL.


21 citations in Web of Science®
26 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:06 Faculty of Arts > Institute of Sociology
Dewey Decimal Classification:300 Social sciences, sociology & anthropology
Uncontrolled Keywords:Diabetic retinopathy; Structural Equation Modeling (SEM); SF-12
Deposited On:08 Mar 2010 14:29
Last Modified:05 Apr 2016 13:50
Funders:Lilly Germany GmbH, Bad Homburg, Germany
Additional Information:The original publication is available at www.springerlink.com
Publisher DOI:10.1007/s00417-008-0960-y
PubMed ID:18925408

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