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Diabetic retinopathy and health-related quality of life


Davidov, Eldad; Breitscheidel, L; Clouth, J; Reips, M; Happich, M (2009). Diabetic retinopathy and health-related quality of life. Graefe's Archive for Clinical and Experimental Ophthalmology, 247(2):267-272.

Abstract

Objective:
To describe the impact of co-morbidities, visual acuity, diabetic retinopathy (DR) grade, and macular edema (ME) on the health-related quality of life (HRQOL) among patients with diabetic retinopathy.

Methods:
Analysis of data of 207 patients with diabetic retinopathy from Germany in 2003. HRQOL assessment was done using the generic (SF-12) questionnaire. It was hypothesized that exogenous variables (co-morbidities, visual acuity impairment, DR, and ME) would have an impact on HRQOL. Using a structural equation modelling procedure, the effects of exogenous variables on endogenous variables physical component summaries (PSC) and mental component summaries (MCS) reflecting HRQOL were tested.

Results:
The number of co-morbidities had a negative effect on visual acuity (b = −0.26, standardized) and a similar negative effect on PCS (b = −0.27). DR grade had a negative effect on visual acuity (b = −0.19) and a positive effect on the variable ME (b = 0.44). ME displayed a negative effect on visual acuity (b = −0.58) and also on MCS (b = −0.29). Visual acuity had a positive effect (b = 0.48) on PCS.

Conclusions:
Presence of DR and ME, visual acuity impairment and patient co-morbidities lead to significant impairment of both the physical and mental components of HRQOL.

Objective:
To describe the impact of co-morbidities, visual acuity, diabetic retinopathy (DR) grade, and macular edema (ME) on the health-related quality of life (HRQOL) among patients with diabetic retinopathy.

Methods:
Analysis of data of 207 patients with diabetic retinopathy from Germany in 2003. HRQOL assessment was done using the generic (SF-12) questionnaire. It was hypothesized that exogenous variables (co-morbidities, visual acuity impairment, DR, and ME) would have an impact on HRQOL. Using a structural equation modelling procedure, the effects of exogenous variables on endogenous variables physical component summaries (PSC) and mental component summaries (MCS) reflecting HRQOL were tested.

Results:
The number of co-morbidities had a negative effect on visual acuity (b = −0.26, standardized) and a similar negative effect on PCS (b = −0.27). DR grade had a negative effect on visual acuity (b = −0.19) and a positive effect on the variable ME (b = 0.44). ME displayed a negative effect on visual acuity (b = −0.58) and also on MCS (b = −0.29). Visual acuity had a positive effect (b = 0.48) on PCS.

Conclusions:
Presence of DR and ME, visual acuity impairment and patient co-morbidities lead to significant impairment of both the physical and mental components of HRQOL.

Citations

21 citations in Web of Science®
26 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:06 Faculty of Arts > Institute of Sociology
Dewey Decimal Classification:300 Social sciences, sociology & anthropology
Uncontrolled Keywords:Diabetic retinopathy; Structural Equation Modeling (SEM); SF-12
Language:English
Date:2009
Deposited On:08 Mar 2010 14:29
Last Modified:05 Apr 2016 13:50
Publisher:Springer
ISSN:0721-832X
Funders:Lilly Germany GmbH, Bad Homburg, Germany
Additional Information:The original publication is available at www.springerlink.com
Publisher DOI:10.1007/s00417-008-0960-y
PubMed ID:18925408
Permanent URL: http://doi.org/10.5167/uzh-29015

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