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Legrand, N; Ploss, A; Balling, R; Becker, P D; Borsotti, C; Brezillon, N; Debarry, J; De Jong, Y; Deng, H; Di Santo, J P; Eisenbarth, S; Eynon, E; Flavell, R A; Guzman, C A; Huntington, N D; Kremsdorf, D; Manns, M P; Manz, M G; Mention, J J; Ott, M; Rathinam, C; Rice , C M; Rongvaux, A; Stevens, S; Spits, H; Strick-Marchand, H; Takizawa, H; van Lent, A U; Wang, C; Weijer, K; Willinger, T; Ziegler, P (2009). Humanized mice for modeling human infectious disease: challenges, progress, and outlook. Cell Host & Microbe, 6(1):5-9.

Full text not available from this repository.

Abstract

Over 800 million people worldwide are infected with hepatitis viruses, human immunodeficiency virus (HIV), and malaria, resulting in more than 5 million deaths annually. Here we discuss the potential and challenges of humanized mouse models for developing effective and affordable therapies and vaccines, which are desperately needed to combat these diseases.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Hematology
DDC:610 Medicine & health
Language:English
Date:23 July 2009
Deposited On:02 Mar 2010 15:35
Last Modified:28 Nov 2013 00:26
Publisher:Elsevier
ISSN:1931-3128
Publisher DOI:10.1016/j.chom.2009.06.006
PubMed ID:19616761
Citations:Web of Science®. Times Cited: 90
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