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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-2931

Richards, S; Bopp, D; et al., (2008). The genome of the model beetle and pest Tribolium castaneum. Nature, 452(7190):949-955.

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Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural products. We describe its genome sequence here. This omnivorous beetle has evolved the ability to interact with a diverse chemical environment, as shown by large expansions in odorant and gustatory receptors, as well as P450 and other detoxification enzymes. Development in Tribolium is more representative of other insects than is Drosophila, a fact reflected in gene content and function. For example, Tribolium has retained more ancestral genes involved in cell–cell communication than Drosophila, some being expressed in the growth zone crucial for axial elongation in short-germ development. Systemic RNA interference in T. castaneum functions differently from that in Caenorhabditis elegans, but nevertheless offers similar power for the elucidation of gene function and identification of targets for selective insect control.

Contributors:Tribolium Genome Sequencing Consortium
Item Type:Journal Article, refereed, original work
Communities & Collections:07 Faculty of Science > Institute of Molecular Life Sciences
DDC:570 Life sciences; biology
Uncontrolled Keywords:Genome sequence, Tribolium castaneum
Date:23 March 2008
Deposited On:05 Aug 2008 17:12
Last Modified:27 Nov 2013 22:07
Publisher:Nature Publishing Group
Publisher DOI:10.1038/nature06784
PubMed ID:18362917
Citations:Web of Science®. Times Cited: 397
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Scopus®. Citation Count: 408

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