UZH-Logo

Multivesicular assemblies as real-world testbeds for embryogenic evolutionary systems


Hadorn, M; Eggenberger Hotz, P (2009). Multivesicular assemblies as real-world testbeds for embryogenic evolutionary systems. In: 4th Australian Conference on Artificial Life (ACAL 2009), Melbourne, Australia, 1 December 2009 - 4 December 2009, 169-178.

Abstract

Embryogenic evolution emulates in silico cell-like entities to get more powerful methods for complex evolutionary tasks. As simulations have to abstract from the biological model, implicit information hidden in its physics is lost. Here, we propose to use cell-like entities as a real-world in vitro testbed. In analogy to evolutionary robotics, where solutions evolved in simulations may be tested in real-world on macroscale, the proposed vesicular testbed would do the same for the embryogenic evolutionary tasks on mesoscale. As a first step towards a vesicular testbed emulating growth, cell division, and cell differentiation, we present a modified vesicle production method, providing custom-tailored chemical cargo, and present a novel self-assembly procedure to provide vesicle aggregates of programmable composition.

Embryogenic evolution emulates in silico cell-like entities to get more powerful methods for complex evolutionary tasks. As simulations have to abstract from the biological model, implicit information hidden in its physics is lost. Here, we propose to use cell-like entities as a real-world in vitro testbed. In analogy to evolutionary robotics, where solutions evolved in simulations may be tested in real-world on macroscale, the proposed vesicular testbed would do the same for the embryogenic evolutionary tasks on mesoscale. As a first step towards a vesicular testbed emulating growth, cell division, and cell differentiation, we present a modified vesicle production method, providing custom-tailored chemical cargo, and present a novel self-assembly procedure to provide vesicle aggregates of programmable composition.

Citations

2 citations in Web of Science®
2 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

41 downloads since deposited on 08 Feb 2010
19 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Conference or Workshop Item (Paper), refereed, original work
Communities & Collections:03 Faculty of Economics > Department of Informatics
Dewey Decimal Classification:000 Computer science, knowledge & systems
Language:English
Event End Date:4 December 2009
Deposited On:08 Feb 2010 14:19
Last Modified:05 Apr 2016 13:53
Publisher:Springer
Series Name:Lecture Notes in Computer Science
Number:5865
ISSN:0302-9743 (P) 1611-3349 (E)
ISBN:978-3-642-10426-8
Additional Information:The original publication is available at www.springerlink.com Proceedings: 4th Australian Conference, ACAL 2009, Melbourne, Australia, December 1-4, 2009
Publisher DOI:10.1007/978-3-642-10427-5_17
Related URLs:http://www.springerlink.com/content/978-3-642-10426-8
Permanent URL: http://doi.org/10.5167/uzh-29863

Download

[img]
Preview
Filetype: PDF (Accepted manuscript)
Size: 1MB
View at publisher

TrendTerms

TrendTerms displays relevant terms of the abstract of this publication and related documents on a map. The terms and their relations were extracted from ZORA using word statistics. Their timelines are taken from ZORA as well. The bubble size of a term is proportional to the number of documents where the term occurs. Red, orange, yellow and green colors are used for terms that occur in the current document; red indicates high interlinkedness of a term with other terms, orange, yellow and green decreasing interlinkedness. Blue is used for terms that have a relation with the terms in this document, but occur in other documents.
You can navigate and zoom the map. Mouse-hovering a term displays its timeline, clicking it yields the associated documents.

Author Collaborations