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Genetic diversity of anaplasma species major surface proteins and implications for anaplasmosis serodiagnosis and vaccine development


de la Fuente, J; Lew, A; Lutz, H; Meli, M L; Hofmann-Lehmann, R; Shkap, V; Molad, T; Mangold, A J; Almazán, C; Naranjo, V; Gortázar, C; Torina, A; Caracappa, S; García-Pérez, A L; Barral, M; Oporto, B; Ceci, L; Carelli, G; Blouin, E F; Kocan, K M (2005). Genetic diversity of anaplasma species major surface proteins and implications for anaplasmosis serodiagnosis and vaccine development. Animal Health Research Reviews, 6(1):75-89.

Abstract

The genus Anaplasma (Rickettsiales: Anaplasmataceae) includes several pathogens of veterinary and human medical importance. An understanding of the diversity of Anaplasma major surface proteins (MSPs), including those MSPs that modulate infection, development of persistent infections, and transmission of pathogens by ticks, is derived in part, by characterization and phylogenetic analyses of geographic strains. Information concerning the genetic diversity of Anaplasma spp. MSPs will likely influence the development of serodiagnostic assays and vaccine strategies for the control of anaplasmosis.

The genus Anaplasma (Rickettsiales: Anaplasmataceae) includes several pathogens of veterinary and human medical importance. An understanding of the diversity of Anaplasma major surface proteins (MSPs), including those MSPs that modulate infection, development of persistent infections, and transmission of pathogens by ticks, is derived in part, by characterization and phylogenetic analyses of geographic strains. Information concerning the genetic diversity of Anaplasma spp. MSPs will likely influence the development of serodiagnostic assays and vaccine strategies for the control of anaplasmosis.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Veterinary Clinic > Department of Farm Animals
Dewey Decimal Classification:570 Life sciences; biology
630 Agriculture
Language:English
Date:2005
Deposited On:19 Aug 2008 09:46
Last Modified:05 Apr 2016 12:25
Publisher:Cambridge Journals
ISSN:1466-2523
Publisher DOI:10.1079/AHR2005104
PubMed ID:16164010
Permanent URL: http://doi.org/10.5167/uzh-3036

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