Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-31473
Jiricny, J (2002). DNA repair: bioinformatics helps reverse methylation damage. Current Biology, 12(24):R846-R848.
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Abstract
Recent work has uncovered a novel DNA repair enzyme: the AlkB protein of Escherichia coli, which oxidises the methyl groups of 1-methyladenine and 3-methylcytosine to hydroxymethyl moieties; the oxidised groups are subsequently released as formaldehyde, regenerating the unmodified bases.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > Institute of Molecular Cancer Research 07 Faculty of Science > Institute of Molecular Cancer Research |
| DDC: | 570 Life sciences; biology |
| Language: | English |
| Date: | 2002 |
| Deposited On: | 09 Jul 2010 16:20 |
| Last Modified: | 24 Nov 2012 15:17 |
| Publisher: | Elsevier |
| ISSN: | 0960-9822 |
| Free access at: | Publisher DOI. An embargo period may apply. |
| Publisher DOI: | 10.1016/S0960-9822(02)01350-7 |
| PubMed ID: | 12498704 |
| WoS Citation Count: | 6 |
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