Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-32670
Spiegelhalder, K; Hornyak, M; Kyle, S D; Paul, D; Blechert, J; Seifritz, E; Hennig, J; Tebartz van Elst, L; Riemann, D; Feige, B (2009). Cerebral correlates of heart rate variations during a spontaneous panic attack in the fMRI scanner. Neurocase, 15(6):527-534.
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We report the first published case study of a suddenly occurring panic attack in a patient with no prior history of panic disorder during combined functional magnetic resonance imaging (fMRI, 1.5 Tesla) and electrocardiogram (ECG) recording. The single case was a 46-year-old woman who developed a panic attack near the planned end of the fMRI acquisition session, which therefore had to be aborted. Correlational analysis of heart rate fluctuations and fMRI data revealed a significant negative association in the left middle temporal gyrus. Additionally, regions-of-interest (ROI) analyses indicated significant positive associations in the left amygdala, and trends towards significance in the right amygdala and left insula.
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > Psychiatric University Hospital Zurich > Clinic for Psychiatry, Psychotherapy, and Psychosomatics|
|DDC:||610 Medicine & health|
|Deposited On:||09 Mar 2010 12:19|
|Last Modified:||28 Jan 2014 15:30|
|Publisher:||Taylor & Francis Group|
|Citations:||Web of Science®. Times Cited: 6|
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