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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-32670

Spiegelhalder, K; Hornyak, M; Kyle, S D; Paul, D; Blechert, J; Seifritz, E; Hennig, J; Tebartz van Elst, L; Riemann, D; Feige, B (2009). Cerebral correlates of heart rate variations during a spontaneous panic attack in the fMRI scanner. Neurocase, 15(6):527-534.

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We report the first published case study of a suddenly occurring panic attack in a patient with no prior history of panic disorder during combined functional magnetic resonance imaging (fMRI, 1.5 Tesla) and electrocardiogram (ECG) recording. The single case was a 46-year-old woman who developed a panic attack near the planned end of the fMRI acquisition session, which therefore had to be aborted. Correlational analysis of heart rate fluctuations and fMRI data revealed a significant negative association in the left middle temporal gyrus. Additionally, regions-of-interest (ROI) analyses indicated significant positive associations in the left amygdala, and trends towards significance in the right amygdala and left insula.


12 citations in Web of Science®
13 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Psychiatric University Hospital Zurich > Clinic for Psychiatry, Psychotherapy, and Psychosomatics
Dewey Decimal Classification:610 Medicine & health
Date:December 2009
Deposited On:09 Mar 2010 11:19
Last Modified:05 Apr 2016 14:02
Publisher:Taylor & Francis Group
Publisher DOI:10.1080/13554790903066909
PubMed ID:19657971

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