Quick Search:

uzh logo
Browse by:

Zurich Open Repository and Archive

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-32753

Knols, R H; de Bruin, E D; Uebelhart, D; Aaronson, N K (2010). The relationship between ambulatory step activity, self-reported physical functioning and standardised timed walking in patients with haematological malignancies. Disability and Rehabilitation, 32(22):1819-1826.

Accepted Version
View at publisher


Purpose. This cross-sectional study investigated the degree of association between the results of ambulatory step activity monitoring (SAM), self-reported physical functioning (SRPF) and the 6-minute standardised walking test (6-MWT) in cancer patients with haematological malignancies.

Method. Assessments of ambulatory SAM, SRPF and 6-MWT were assessed in 102 patients up to 122 days (mean 78+35) after haematopoietic stem cell transplantation (HSCT). To determine the association between measures of walking, the Pearson product moment correlation coefficient (r) including the 95%CI and the r2 were calculated. Simple
linear regression analyses were performed to estimate the ambulatory step activity from SRPF and the 6-MWT.

Results. The average age was 47 years (+12) and body mass index 23.4 (+4). The correlations were low between
ambulatory SAM outputs and SRPF (ranging from70.32 to 0.34, p50.01), and very low between SAM outputs and 6-MWT, (ranging from 0.21 to 0.24). The correlation between SRPF and the 6-MWT was low (0.33, p50.01). The correlation between SRPF and the 6-MWT was low (0.33, p50.01). The 95%CIs were quite narrow around r. The shared variance (r2) between the SAM and SPPF ranged between 4% and 11% and the shared variance between the SAM and 6-MWT ranged between 0.5% and 18%. Linear regression yielded weak relationships and large standard errors of estimate between the SAM, SRPF and 6-MWT.

Conclusions. SRPF and the 6-MWT do not reflect daily walking activity. In clinical use (e.g. to evaluate the effects of a rehabilitation program), ambulatory step activity outputs can be considered an additional outcome to assess day-to-day walking activity in patients with haematological cancer after HSCT.


4 citations in Web of Science®
4 citations in Scopus®
Google Scholar™



78 downloads since deposited on 01 Apr 2010
18 downloads since 12 months

Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Rheumatology Clinic and Institute of Physical Medicine
Dewey Decimal Classification:610 Medicine & health
Date:March 2010
Deposited On:01 Apr 2010 12:47
Last Modified:05 Apr 2016 14:02
Publisher:Informa Healthcare
Publisher DOI:10.3109/09638281003734482
PubMed ID:20337514

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page