Quick Search:

uzh logo
Browse by:
bullet
bullet
bullet
bullet

Zurich Open Repository and Archive 

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-3285

Wiesmann, M; Ishai, A (2008). Recollection- and familiarity-based decisions reflect memory strength. Frontiers in Systems Neuroscience, 2(1):Published Online.

[img]
Preview
PDF
2MB

Abstract

We used event-related fMRI to investigate whether recollection- and familiarity-based memory judgments are modulated by the degree of visual similarity between old and new art paintings. Subjects performed a flower detection task, followed by a Remember/Know/New surprise memory test. The old paintings were randomly presented with new paintings, which were either visually similar or visually different. Consistent with our prediction, subjects were significantly faster and more accurate to reject new, visually different paintings than new, visually similar ones. The proportion of false alarms, namely remember and know responses to new paintings, was significantly reduced with decreased visual similarity. The retrieval task evoked activation in multiple visual, parietal and prefrontal regions, within which remember judgments elicited stronger activation than know judgments. New, visually different paintings evoked weaker activation than new, visually similar items in the intraparietal sulcus. Contrasting recollection with familiarity revealed activation predominantly within the precuneus, where the BOLD response elicited by recollection peaked significantly earlier than the BOLD response evoked by familiarity judgments. These findings suggest that successful memory retrieval of pictures is mediated by activation in a distributed cortical network, where memory strength is manifested by differential hemodynamic profiles. Recollection- and familiarity-based memory decisions may therefore reflect strong memories and weak memories, respectively.

Item Type:Journal Article, refereed, original work
Communities & Collections:07 Faculty of Science > Institute of Neuroinformatics
04 Faculty of Medicine > University Hospital Zurich > Clinic for Neuroradiology
DDC:570 Life sciences; biology
610 Medicine & health
Language:English
Date:May 2008
Deposited On:08 Sep 2008 09:24
Last Modified:23 Nov 2012 15:38
Publisher:Frontiers Research Foundation
ISSN:1662-5137
Additional Information:© 2008 Wiesmann and Ishai. This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.
Publisher DOI:10.3389/neuro.06.001.2008
Other Identification Number:ini:13117
Citations:Google Scholar™
Scopus®. Citation Count: 9

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page