Quick Search:

uzh logo
Browse by:

Zurich Open Repository and Archive

Maintenance: Tuesday, July the 26th 2016, 07:00-10:00

ZORA's new graphical user interface will be relaunched (For further infos watch out slideshow ZORA: Neues Look & Feel). There will be short interrupts on ZORA Service between 07:00am and 10:00 am. Please be patient.

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-33519

Ess, S; Savidan, A; Frick, H; Rageth, C H; Vlastos, G; Lütolf, U; Thürlimann, B (2010). Geographic variation in breast cancer care in Switzerland. Cancer Epidemiology, 34(2):116-121.

[img] PDF - Registered users only
View at publisher


PURPOSE: Regional disparities in breast cancer outcomes have been reported in Switzerland. The purpose of this study is to investigate geographic variation in early diagnosis and management of breast cancer. METHODS: We used data from a representative sample of 4820 women diagnosed with invasive breast cancer between January 1, 2003 and December 31, 2005 identified by seven Swiss population based cancer registries. We collected retrospectively detailed information on mode of detection, tumor characteristics and treatments. Differences across geographic regions were tested for statistical significance using chi-square tests and uni- and multivariate logistic regression. RESULTS: Considerable disparities in early detection and management of early breast cancer were found across regions. In particular, the proportion of early detected cancer varied from 43% in Valais to 27% in St. Gallen-Appenzell. Mastectomy rates varied from 24% in Geneva to 38% in St. Gallen-Appenzell and Grisons-Glarus. Higher reconstruction rates were observed in regions with lower rates of mastectomy. The use of sentinel node procedure in patients with nodal negative disease was high in Geneva and low in Eastern Switzerland. Differences in compliance with recommendations on the use of endocrine therapy and chemotherapy were less pronounced but statistically significant. CONCLUSIONS: This analysis shows considerable geographic variation in breast cancer care in a health system characterized by high expenditures, universal access to services and high decentralization. Further study into the causes and effects of this variation on short- and long term patient outcomes is needed.


16 citations in Web of Science®
21 citations in Scopus®
Google Scholar™



4 downloads since deposited on 15 May 2010
0 downloads since 12 months

Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Radiation Oncology
Dewey Decimal Classification:610 Medicine & health
Uncontrolled Keywords:Breast cancer; Practice guideline; Diagnostic techniques and procedures; Breast surgery; Mastectomy; Sentinel lymph node biopsy; Systemic therapy; Radiotherapy; Health care disparities; Retrospective study
Date:April 2010
Deposited On:15 May 2010 19:12
Last Modified:05 Apr 2016 14:05
Publisher DOI:10.1016/j.canep.2010.01.008
PubMed ID:20185382

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page