UZH-Logo

Increased bone marrow activity on F-18-FDG PET/CT in granulocyte colony stimulating factor producing anaplastic thyroid carcinoma


Zweifel, M; Stenner-Liewen, F; Weber, A; Samaras, P; Zaugg, K; Knuth, A; Soyka, J D (2010). Increased bone marrow activity on F-18-FDG PET/CT in granulocyte colony stimulating factor producing anaplastic thyroid carcinoma. Clinical Nuclear Medicine, 35(2):103-104.

Abstract

A 57-year-old man presented with jugular swelling. A leukocytosis of 50,000 WBC/μL (95% neutrophils) was found. PET/CT demonstrated increased fluorine-18-fluorodeoxyglucose uptake in the cervical/retrosternal mass, in the bone marrow, and in the enlarged spleen. Bone marrow biopsy confirmed myeloid hypercellularity with a left shift, but there were no signs of dysplasia and no evidence of tumor infiltration. Pathology of the thyroidectomy specimen confirmed an anaplastic thyroid carcinoma. Serum granulocyte-colony stimulating factor was elevated to 38.8 pg/mL (normal range, <0.6 pg/mL); granulocyte/macrophage-colony stimulating factor was normal (<2 pg/mL).

A 57-year-old man presented with jugular swelling. A leukocytosis of 50,000 WBC/μL (95% neutrophils) was found. PET/CT demonstrated increased fluorine-18-fluorodeoxyglucose uptake in the cervical/retrosternal mass, in the bone marrow, and in the enlarged spleen. Bone marrow biopsy confirmed myeloid hypercellularity with a left shift, but there were no signs of dysplasia and no evidence of tumor infiltration. Pathology of the thyroidectomy specimen confirmed an anaplastic thyroid carcinoma. Serum granulocyte-colony stimulating factor was elevated to 38.8 pg/mL (normal range, <0.6 pg/mL); granulocyte/macrophage-colony stimulating factor was normal (<2 pg/mL).

Citations

7 citations in Web of Science®
4 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

2 downloads since deposited on 06 Jul 2010
0 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Radiation Oncology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Oncology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:February 2010
Deposited On:06 Jul 2010 21:53
Last Modified:05 Apr 2016 14:10
Publisher:Lippincott Wiliams & Wilkins
ISSN:0363-9762
Publisher DOI:10.1097/RLU.0b013e3181c7be63
PubMed ID:20090458
Permanent URL: http://doi.org/10.5167/uzh-34655

Download

[img]Filetype: PDF - Registered users only
Size: 139kB
View at publisher

TrendTerms

TrendTerms displays relevant terms of the abstract of this publication and related documents on a map. The terms and their relations were extracted from ZORA using word statistics. Their timelines are taken from ZORA as well. The bubble size of a term is proportional to the number of documents where the term occurs. Red, orange, yellow and green colors are used for terms that occur in the current document; red indicates high interlinkedness of a term with other terms, orange, yellow and green decreasing interlinkedness. Blue is used for terms that have a relation with the terms in this document, but occur in other documents.
You can navigate and zoom the map. Mouse-hovering a term displays its timeline, clicking it yields the associated documents.

Author Collaborations