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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-34655

Zweifel, M; Stenner-Liewen, F; Weber, A; Samaras, P; Zaugg, K; Knuth, A; Soyka, J D (2010). Increased bone marrow activity on F-18-FDG PET/CT in granulocyte colony stimulating factor producing anaplastic thyroid carcinoma. Clinical Nuclear Medicine, 35(2):103-104.

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A 57-year-old man presented with jugular swelling. A leukocytosis of 50,000 WBC/μL (95% neutrophils) was found. PET/CT demonstrated increased fluorine-18-fluorodeoxyglucose uptake in the cervical/retrosternal mass, in the bone marrow, and in the enlarged spleen. Bone marrow biopsy confirmed myeloid hypercellularity with a left shift, but there were no signs of dysplasia and no evidence of tumor infiltration. Pathology of the thyroidectomy specimen confirmed an anaplastic thyroid carcinoma. Serum granulocyte-colony stimulating factor was elevated to 38.8 pg/mL (normal range, <0.6 pg/mL); granulocyte/macrophage-colony stimulating factor was normal (<2 pg/mL).


7 citations in Web of Science®
4 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Radiation Oncology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Oncology
Dewey Decimal Classification:610 Medicine & health
Date:February 2010
Deposited On:06 Jul 2010 21:53
Last Modified:05 Apr 2016 14:10
Publisher:Lippincott Wiliams & Wilkins
Publisher DOI:10.1097/RLU.0b013e3181c7be63
PubMed ID:20090458

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