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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-34825

Dettmer, M; Hegemann, I; Hegemann, S C A (2010). Extraintestinal Crohn's Disease Mimicking Autoimmune Inner Ear Disease: A Histopathological Approach. Audiology & Neuro-Otology, 16(1):36-40.

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Abstract

Patients with autoimmune inner ear disease develop rapidly progressive sensorineural hearing loss over a period of several weeks or months, often accompanied by vestibular loss. This disease can occur as a distinct clinical entity or in association with an underlying autoimmune disorder. Treatment comprises immunosuppression by corticosteroids, cytostatic drugs or tumor necrosis factor-alpha antagonists. We report histopathological and immunohistochemical findings of the inner ear of a patient with a granulomatous inner ear disease suffering from Crohn's disease that was nonresponsive to treatment and who underwent surgery for bilateral cochlear implants.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic and Policlinic for Internal Medicine
04 Faculty of Medicine > University Hospital Zurich > Clinic for Otorhinolaryngology
04 Faculty of Medicine > University Hospital Zurich > Institute of Surgical Pathology
DDC:610 Medicine & health
Language:English
Date:2010
Deposited On:06 Jul 2010 14:44
Last Modified:09 Dec 2013 16:19
Publisher:Karger
ISSN:1420-3030
Publisher DOI:10.1159/000315063
PubMed ID:20523038
Citations:Web of Science®. Times Cited: 2
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Scopus®. Citation Count: 3

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