Quick Search:

uzh logo
Browse by:
bullet
bullet
bullet
bullet

Zurich Open Repository and Archive 

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-34845

Janach, M; Kühne, A; Seifert, Burkhardt; French, L E; Ballmer-Weber, B; Hofbauer, G F L (2010). Changing delayed-type sensitizations to the baseline series allergens over a decade at the Zurich University Hospital. Contact Dermatitis, 63(1):42-78.

[img]PDF - Registered users only
478Kb

Abstract

BACKGROUND: Patch testing detects delayed-type sensitizations and may show changes in prevalence over time. OBJECTIVES: To compare sensitization prevalence to our baseline series allergens during the years 2000-2004 to results from 1990 to 1994. METHODS: We analysed baseline patch test series allergens from 2000 through 2004. RESULTS: 4094 individuals were patch tested to the baseline series (mean age 45.4 years, males 41.7%). The highest sensitization rates were found for nickel sulfate (19.3%), fragrance mix (10.4%) and Myroxylon pereirae (7.8%). Compared to 1990-1994, methylchloroisothiazolinone (and) methylisothiazoline (MCI/MI) and neomycin sulfate sensitization decreased and lanolin alcohol, thiuram mix and ammoniated mercury sensitization increased. CONCLUSIONS: Current sensitization rates are similar to those across Europe. Reduced sensitizations to MCI/MI and neomycin sulfate and increased sensitizations to thiuram mix and ammoniated mercury chloride may well be because of changes in exposure. The current group comprises a higher proportion affected by leg dermatitis and may thus explain the higher sensitization to lanolin alcohol. Comparing patch results over time shows important changes in sensitization prevalence.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Social and Preventive Medicine
04 Faculty of Medicine > University Hospital Zurich > Dermatology Clinic
DDC:610 Medicine & health
Language:English
Date:June 2010
Deposited On:15 Jul 2010 10:49
Last Modified:02 Mar 2014 06:28
Publisher:Wiley-Blackwell
ISSN:0105-1873
Publisher DOI:10.1111/j.1600-0536.2010.01727.x
PubMed ID:20597933
Citations:Google Scholar™

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page