Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-35821
Fleisch, V C; Neuhauss, S C F (2010). Parallel visual cycles in the zebrafish retina. Progress in Retinal and Eye Research, 29(6):476-486.
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Vertebrate vision necessitates continuous recycling of the chromophore 11-cis retinal (RAL). The classical (or canonical) visual cycle employs a number of enzymes located in the photoreceptor outer segment and RPE (retinal pigment epithelium) of the retina to regenerate 11-cis RAL from all-trans RAL. Cone-dominant species are believed to utilize a second, intra-retinal, pathway for 11-cis RAL generation, involving retinal Müller glia cells. This review summarizes the efforts made in zebrafish to gain a better understanding of the role of these two visual cycles for rod and cone photoreceptor chromophore recycling.
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|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||07 Faculty of Science > Institute of Molecular Life Sciences|
|DDC:||570 Life sciences; biology|
|Uncontrolled Keywords:||Visual Cycle, RetinoidCycle, Zebrafish, Cone Photoreceptor, Müller GliaCell, CRALBP|
|Date:||19 November 2010|
|Deposited On:||09 Nov 2010 12:23|
|Last Modified:||27 Nov 2013 23:50|
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