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Hemorrhage associated with hepatic artery pseudoaneurysms after regional chemotherapy with floxuridine: case report


Samaras, P; Pfammatter, T; Pestalozzi, B C (2008). Hemorrhage associated with hepatic artery pseudoaneurysms after regional chemotherapy with floxuridine: case report. International Seminars in Surgical Oncology, 5:17:1-5.

Abstract

Pseudoaneurysms of the hepatic artery are a rare complication in patients with primary or secondary liver tumors treated with intra-arterial chemotherapy. We present
two patients who developed this complication after placement of a catheter system into the gastroduodenal artery and initiation of regional chemotherapy with floxuridine. Diagnosis was made after symptomatic bleeding occurred, necessitating emergency angiography with coil embolization. Pseudoaneurysms usually occur after mechanical damage of the vessel wall, but the chemical toxicity of floxuridine may add to the development of vascular impairment.

Pseudoaneurysms of the hepatic artery are a rare complication in patients with primary or secondary liver tumors treated with intra-arterial chemotherapy. We present
two patients who developed this complication after placement of a catheter system into the gastroduodenal artery and initiation of regional chemotherapy with floxuridine. Diagnosis was made after symptomatic bleeding occurred, necessitating emergency angiography with coil embolization. Pseudoaneurysms usually occur after mechanical damage of the vessel wall, but the chemical toxicity of floxuridine may add to the development of vascular impairment.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Oncology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Diagnostic and Interventional Radiology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2008
Deposited On:29 Sep 2008 13:06
Last Modified:13 Sep 2016 07:29
Publisher:BioMed Central
ISSN:1477-7800
Additional Information:Free full text article
Publisher DOI:10.1186/1477-7800-5-17
Official URL:http://www.issoonline.com/content/pdf/1477-7800-5-17.pdf
PubMed ID:18620556
Permanent URL: http://doi.org/10.5167/uzh-3629

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