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Fine-tuning the RAS signaling pathway: Zn(2+) makes the difference.


Hajnal, A (2002). Fine-tuning the RAS signaling pathway: Zn(2+) makes the difference. Molecular Cell, 9(5):927-928.

Abstract

In the May, 2002 issue of Developmental Cell, Bruinsma et al. report that the CDF-1 cation diffusion facilitator protein is required for efficient Ras-mediated signaling in C. elegans. CDF-1 reduces intracellular Zn(2+) levels, indicating an inhibitory effect of Zn(2+) on the Ras pathway.

Abstract

In the May, 2002 issue of Developmental Cell, Bruinsma et al. report that the CDF-1 cation diffusion facilitator protein is required for efficient Ras-mediated signaling in C. elegans. CDF-1 reduces intracellular Zn(2+) levels, indicating an inhibitory effect of Zn(2+) on the Ras pathway.

Citations

3 citations in Web of Science®
6 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed
Communities & Collections:07 Faculty of Science > Institute of Molecular Life Sciences
Dewey Decimal Classification:570 Life sciences; biology
Language:English
Date:1 May 2002
Deposited On:11 Feb 2008 12:14
Last Modified:05 Apr 2016 12:13
Publisher:Elsevier
ISSN:1097-2765
Publisher DOI:https://doi.org/10.1016/S1097-2765(02)00535-X
PubMed ID:12049729

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