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Hermann, M; Enseleit, F; Ruschitzka, F T (2005). Anti-inflammatory strategies in hypertension: focus on COX-1 and COX-2. Current Hypertension Reports, 7(1):52-60.

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An increasing body of evidence suggests that elevated levels of blood pressure may induce a proinflammatory response. Indeed, both C-reactive protein and blood pressure are independent determinants of cardiovascular risk, and, in combination, each parameter has additional predictive value. Hence, strategies targeted to lower blood pressure and reduce vascular inflammation may potentially provide clinical benefit. In this review, we discuss the role of chronic low-grade inflammation in the context of cardiovascular disease with a focus on roles of cyclooxygenase-1 and -2 in potential anti-inflammatory treatment strategies.

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiology
DDC:610 Medicine & health
Deposited On:04 Mar 2011 09:10
Last Modified:28 Nov 2013 01:02
Publisher DOI:10.1007/s11906-005-0055-7
PubMed ID:15683587
Citations:Web of Science®. Times Cited: 2
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Scopus®. Citation Count: 2

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