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Primary anaplastic ganglioglioma with a small-cell glioblastoma component


Schittenhelm, J; Reifenberger, G; Ritz, R; Nägele, T; Weller, M; Pantazis, G; Capper, D; Beschorner, R; Meyermann, R; Mittelbronn, M (2008). Primary anaplastic ganglioglioma with a small-cell glioblastoma component. Clinical Neuropathology, 27(2):91-95.

Abstract

Gangliogliomas usually present as benign tumors corresponding to World Health Organization (WHO) Grade I. Very rarely, gangliogliomas show histological features of malignancy and are then classified as anaplastic gangliogliomas of WHO Grade III or IV. In most cases, anaplastic gangliogliomas developed after radiation therapy or progression from a pre-existing low-grade ganglioglioma. Here, we report the case of a 77-year-old male patient who was operated on a primary ganglioglioma with a highly anaplastic glial component corresponding to a small-cell glioblastoma. To our knowledge, this is the first reported case of a primary anaplastic ganglioglioma with a small-cell glioblastoma component.

Gangliogliomas usually present as benign tumors corresponding to World Health Organization (WHO) Grade I. Very rarely, gangliogliomas show histological features of malignancy and are then classified as anaplastic gangliogliomas of WHO Grade III or IV. In most cases, anaplastic gangliogliomas developed after radiation therapy or progression from a pre-existing low-grade ganglioglioma. Here, we report the case of a 77-year-old male patient who was operated on a primary ganglioglioma with a highly anaplastic glial component corresponding to a small-cell glioblastoma. To our knowledge, this is the first reported case of a primary anaplastic ganglioglioma with a small-cell glioblastoma component.

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8 citations in Web of Science®
9 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Neurology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:March 2008
Deposited On:19 Sep 2008 11:51
Last Modified:05 Apr 2016 12:28
Publisher:Dustri-Verlag Dr. Karl Feistle
ISSN:0722-5091
Official URL:http://www.dustri.com/nc/journals-in-english/mag/clinical-neuropathology/vol/volume-27/issue/marchapril.html
PubMed ID:18402388
Permanent URL: http://doi.org/10.5167/uzh-3868

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