Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-39517
Brown, S A; Pagani, L; Cajochen, C; Eckert, A (2011). Systemic and cellular reflections on ageing and the circadian oscillator - A mini-review. Gerontology, 57(5):427-434.
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From circulation to digestion to excretion, a circadian clock synchronizes most aspects of mammalian physiology with the solar day. During normal ageing, this daily coordination gradually erodes, and during pathological ageing such erosion is exacerbated. Recent experiments suggest that therapies aimed at sustaining circadian function increase quality of life in elderly patients. Hence, a better understanding of the interactions between the circadian clock and ageing - at both cellular and systemic levels - could lead to direct benefits for aged individuals.
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|Item Type:||Journal Article, refereed, further contribution|
|Communities & Collections:||04 Faculty of Medicine > Institute of Pharmacology and Toxicology|
|DDC:||570 Life sciences; biology
610 Medicine & health
|Deposited On:||10 Jan 2011 09:47|
|Last Modified:||06 Feb 2014 03:43|
|Free access at:||Publisher DOI. An embargo period may apply.|
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