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Vollenweider, F X; Kometer, M (2010). The neurobiology of psychedelic drugs: implications for the treatment of mood disorders. Nature Reviews. Neuroscience, 11(9):642-651.

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Abstract

After a pause of nearly 40 years in research into the effects of psychedelic drugs, recent advances in our understanding of the neurobiology of psychedelics, such as lysergic acid diethylamide (LSD), psilocybin and ketamine have led to renewed interest in the clinical potential of psychedelics in the treatment of various psychiatric disorders. Recent behavioural and neuroimaging data show that psychedelics modulate neural circuits that have been implicated in mood and affective disorders, and can reduce the clinical symptoms of these disorders. These findings raise the possibility that research into psychedelics might identify novel therapeutic mechanisms and approaches that are based on glutamate-driven neuroplasticity.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Psychiatric University Hospital Zurich > Clinic for Psychiatry, Psychotherapy, and Psychosomatics
DDC:610 Medicine & health
Language:English
Date:2010
Deposited On:24 Jan 2011 20:09
Last Modified:27 Nov 2013 18:03
Publisher:Nature Publishing Group
ISSN:1471-003X
Publisher DOI:10.1038/nrn2884
PubMed ID:20717121
Citations:Web of Science®. Times Cited: 52
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Scopus®. Citation Count: 53

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