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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-41672

Rozenberg, I; Sluka, S H M; Rohrer , L; Hofmann, J; Becher, B; Akhmedov, A; Soliz, J; Mocharla, P; Borén, J; Johansen, P; Steffel, J; Watanabe, T; Lüscher, T F; Tanner, F C (2010). Histamine H1 receptor promotes atherosclerotic lesion formation by increasing vascular permeability for low-density lipoproteins. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(5):923-930.

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Abstract

These data indicate that H1 but not H2 receptor activation drives the formation of atherosclerotic lesions through an increased vascular permeability for LDL, which is associated with an enhanced secondary aortic and systemic inflammation. These data open novel perspectives for the prevention and treatment of atherosclerotic vascular disease.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of Clinical Chemistry
04 Faculty of Medicine > University Hospital Zurich > Dermatology Clinic
04 Faculty of Medicine > University Hospital Zurich > Institute of Experimental Immunology
DDC:570 Life sciences; biology
610 Medicine & health
540 Chemistry
Date:2010
Deposited On:06 Jan 2011 15:08
Last Modified:27 Nov 2013 18:21
Publisher:Lippincott Wiliams & Wilkins
ISSN:1079-5642
Publisher DOI:10.1161/ATVBAHA.109.201079
PubMed ID:20203300
Citations:Web of Science®. Times Cited: 19
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Scopus®. Citation Count: 20

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