Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-41672
Rozenberg, I; Sluka, S H M; Rohrer , L; Hofmann, J; Becher, B; Akhmedov, A; Soliz, J; Mocharla, P; Borén, J; Johansen, P; Steffel, J; Watanabe, T; Lüscher, T F; Tanner, F C (2010). Histamine H1 receptor promotes atherosclerotic lesion formation by increasing vascular permeability for low-density lipoproteins. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(5):923-930.
![[img]](http://www.zora.uzh.ch/style/images/fileicons/application_pdf.png) | PDF - Registered users only 5Mb |
Abstract
These data indicate that H1 but not H2 receptor activation drives the formation of atherosclerotic lesions through an increased vascular permeability for LDL, which is associated with an enhanced secondary aortic and systemic inflammation. These data open novel perspectives for the prevention and treatment of atherosclerotic vascular disease.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > University Hospital Zurich > Institute of Clinical Chemistry 04 Faculty of Medicine > University Hospital Zurich > Dermatology Clinic 04 Faculty of Medicine > University Hospital Zurich > Institute of Experimental Immunology |
| DDC: | 570 Life sciences; biology 610 Medicine & health 540 Chemistry |
| Date: | 2010 |
| Deposited On: | 06 Jan 2011 16:08 |
| Last Modified: | 23 Nov 2012 14:06 |
| Publisher: | Lippincott Wiliams & Wilkins |
| ISSN: | 1079-5642 |
| Publisher DOI: | 10.1161/ATVBAHA.109.201079 |
| PubMed ID: | 20203300 |
Users (please log in): suggest update or correction for this item
Repository Staff Only: item control page
