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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-42155

Soyka, J D; Strobel, K; Veit-Haibach, P; Schaefer, N G; Schmid, D T; Tschopp, A; Hany, T F (2010). Influence of bowel preparation before 18F-FDG PET/CT on physiologic 18F-FDG activity in the intestine. Journal of Nuclear Medicine, 51(4):507-510.

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Our objective was to investigate the use of bowel preparation before (18)F-FDG PET/CT to reduce intestinal (18)F-FDG uptake.

METHODS: Sixty-five patients with abdominal neoplasias were assigned either to a bowel-preparation group (n = 26) or to a native group (n = 39). (18)F-FDG activity was measured in the small intestine and the colon.

RESULTS: In the 26 patients with bowel preparation, average maximal standardized uptake value (SUVmax) was 3.5 in the small intestine and 4.4 in the colon. In the 39 patients without bowel preparation, average SUVmax was 2.6 in the small intestine and 2.7 in the colon. (18)F-FDG activity impaired diagnosis in 6 patients (23%) in the bowel-preparation group and 11 patients (28%) in the native group (P = 0.5). SUVmax in the colon was significantly higher in the bowel-preparation group (P = 0.002), but SUVmax in the small intestine did not significantly differ between the 2 groups (P = 0.088).

CONCLUSION: Bowel preparation increases (18)F-FDG activity in the large intestine and is therefore not useful before PET/CT..

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Epidemology, Biostatistics and Prevention Institute (EBPI)
04 Faculty of Medicine > University Hospital Zurich > Clinic for Nuclear Medicine
DDC:610 Medicine & health
Deposited On:12 Jan 2011 14:17
Last Modified:11 Jan 2013 07:34
Publisher:Society of Nuclear Medicine
Publisher DOI:10.2967/jnumed.109.071001
PubMed ID:20237041
Citations:Google Scholar™
Scopus®. Citation Count: 10

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