Quick Search:

uzh logo
Browse by:
bullet
bullet
bullet
bullet

Zurich Open Repository and Archive

Baumueller, S; Alkadhi, H; Stolzmann, P; Frauenfelder, T; Goetti, R; Schertler, T; Plass, A; Falk, V; Feuchtner, G; Scheffel, H; Desbiolles, L; Leschka, S (2011). Computed tomography of the lung in the high-pitch mode: Is breath holding still required? Investigative Radiology, 46(4):240-245.

Full text not available from this repository.

View at publisher

Abstract

OBJECTIVES:: To prospectively investigate whether the high-pitch mode (HPM) for computed tomography (CT) enables the diagnostic visualization of the lung parenchyma without suspended respiration. MATERIALS AND METHODS:: A total of 40 consecutive patients (age, 67 ± 11 years) underwent 128-slice dual-source CT of the chest including nonenhanced, arterial, and venous phase of contrast. CT was performed in the HPM with a pitch of 3.2 during continuous breathing (group A) and during breath-hold (group B), and at standard pitch of 1 during deep-inspiratory breath-hold (group C). The 3 protocols were scanned in a random order in each patient. Two blinded readers independently assessed the image quality of 5 regions in both the lungs using a semiquantitative 3-point score. Image noise was measured as the standard deviation of attenuation. Presence and size of pulmonary nodules were noted and measured on each CT dataset. Lung volume was measured using dedicated semi-automated segmentation software. RESULTS:: Interobserver agreement for image quality ratings was excellent (κ = 0.91). There were no significant differences in the number of lung regions having an image quality other than excellent between group A (2.5%) and B (1.5%, P = 0.48), whereas significantly less regions had impaired image quality in group B compared with group C (5.5%, P < 0.01). Image quality impairment in group C was because of breathing in 36% and cardiac pulsation in 64%. Image noise in group C (9 ± 2 HU) was significantly lower than that in group B (30 ± 2 HU, P < 0.001) whereas no significant difference was found between group A and B (P = 0.52). There were no significant differences for the depiction (P = 1.0) and size (P = 0.94) of lung nodules among the 3 modes. Average lung volume in group A was 75% ± 15% of that in deep inspiration (group B/C) being significantly smaller (P < 0.05). Estimated effective radiation doses in group C and group B were 5.8 ± 0.5 mSv and 1.6 ± 0.1 mSv, respectively. CONCLUSIONS:: CT of the lung can be accomplished using the HPM at a low radiation dose with a diagnostic image quality even without suspended respiration.

Citations

21 citations in Web of Science®
21 citations in Scopus®
Google Scholar™

Altmetrics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiovascular Surgery
04 Faculty of Medicine > University Hospital Zurich > Clinic for Diagnostic and Interventional Radiology
DDC:610 Medicine & health
Language:English
Date:2011
Deposited On:13 Jan 2011 16:24
Last Modified:27 Nov 2013 22:04
Publisher:Lippincott Wiliams & Wilkins
ISSN:0020-9996
Publisher DOI:10.1097/RLI.0b013e3181feee1a
PubMed ID:21217528

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page