Quick Search:

uzh logo
Browse by:

Zurich Open Repository and Archive

Maintenance: Tuesday, July the 26th 2016, 07:00-10:00

ZORA's new graphical user interface will be relaunched (For further infos watch out slideshow ZORA: Neues Look & Feel). There will be short interrupts on ZORA Service between 07:00am and 10:00 am. Please be patient.

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-42316

Rossaint, R; Bouillon, B; Cerny, V; Coats, T J; Duranteau, J; Fernández-Mondéjar, E; Hunt, B J; Komadina, R; Nardi, G; Neugebauer, E; Ozier, Y; Riddez, L; Schultz, A; Stahel, P F; Vincent, J L; Spahn, D R (2010). Management of bleeding following major trauma: an updated European guideline. Critical Care, 14(2):R52.

View at publisher


INTRODUCTION: Evidence-based recommendations are needed to guide the acute management of the bleeding trauma patient, which when implemented may improve patient outcomes.

METHODS: The multidisciplinary Task Force for Advanced Bleeding Care in Trauma was formed in 2005 with the aim of developing a guideline for the management of bleeding following severe injury. This document presents an updated version of the guideline published by the group in 2007. Recommendations were formulated using a nominal group process, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) hierarchy of evidence and based on a systematic review of published literature.

RESULTS: Key changes encompassed in this version of the guideline include new recommendations on coagulation support and monitoring and the appropriate use of local haemostatic measures, tourniquets, calcium and desmopressin in the bleeding trauma patient. The remaining recommendations have been reevaluated and graded based on literature published since the last edition of the guideline. Consideration was also given to changes in clinical practice that have taken place during this time period as a result of both new evidence and changes in the general availability of relevant agents and technologies.

CONCLUSIONS: This guideline provides an evidence-based multidisciplinary approach to the management of critically injured bleeding trauma patients.


297 citations in Web of Science®
406 citations in Scopus®
Google Scholar™



152 downloads since deposited on 17 Jan 2011
21 downloads since 12 months

Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of Anesthesiology
Dewey Decimal Classification:610 Medicine & health
Deposited On:17 Jan 2011 13:10
Last Modified:05 Apr 2016 14:35
Publisher:BioMed Central
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:10.1186/cc8943
PubMed ID:20370902

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page