Full text not available from this repository.
A lipid bilayer with gigaohm resistance was fabricated over a single 800 nm pore in a Si3N4 chip using 50 nm liposomes. The nanopore was prefilled with a polyelectrolyte multilayer (PEM) that triggered the spontaneous fusion of the lipid vesicles. Pore-forming peptide melittin was incorporated in the bilayer, and single channel activities were monitored for a period of 2.5 weeks. The long lifetime of the system enabled the observation of the time-dependent stabilization effect of the melittin open state upon bias application.
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > Institute of Biomedical Engineering|
610 Medicine & health
|Deposited On:||27 Jan 2011 17:23|
|Last Modified:||27 Nov 2013 21:39|
|Publisher:||American Chemical Society|
|Citations:||Web of Science®. Times cited: 12|
Users (please log in): suggest update or correction for this item
Repository Staff Only: item control page