Quick Search:

uzh logo
Browse by:

Zurich Open Repository and Archive

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-43515

Haberthür, D; Hintermüller, C; Marone, F; Schittny, J C; Stampanoni, M (2010). Radiation dose optimized lateral expansion of the field of view in synchrotron radiation X-ray tomographic microscopy. Journal of Synchrotron Radiation, 17(5):590-599.

PDF (Verlags-PDF)
View at publisher


Volumetric data at micrometer level resolution can be acquired within a few minutes using synchrotron-radiation-based tomographic microscopy. The field of view along the rotation axis of the sample can easily be increased by stacking several tomograms, allowing the investigation of long and thin objects at high resolution. On the contrary, an extension of the field of view in the perpendicular direction is non-trivial. This paper presents an acquisition protocol which increases the field of view of the tomographic dataset perpendicular to its rotation axis. The acquisition protocol can be tuned as a function of the reconstruction quality and scanning time. Since the scanning time is proportional to the radiation dose imparted to the sample, this method can be used to increase the field of view of tomographic microscopy instruments while optimizing the radiation dose for radiation-sensitive samples and keeping the quality of the tomographic dataset on the required level. This approach, dubbed wide-field synchrotron radiation tomographic microscopy, can increase the lateral field of view up to five times. The method has been successfully applied for the three-dimensional imaging of entire rat lung acini with a diameter of 4.1 mm at a voxel size of 1.48 microm.


14 citations in Web of Science®
16 citations in Scopus®
Google Scholar™



35 downloads since deposited on 30 Jan 2011
14 downloads since 12 months

Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Biomedical Engineering
Dewey Decimal Classification:170 Ethics
610 Medicine & health
Deposited On:30 Jan 2011 20:24
Last Modified:05 Apr 2016 14:39
Publisher:International Union of Crystallography
Publisher DOI:10.1107/S0909049510019618
PubMed ID:20724780

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page