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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-43937

Thoma, D S; Jung, R E; Schneider, D; Cochran, D L; Ender, A; Jones, A A; Görlach, C; Uebersax, L; Graf-Hausner, U; Hämmerle, C H F (2010). Soft tissue volume augmentation by the use of collagen-based matrices: a volumetric analysis. Journal of Clinical Periodontology, 37(7):659-666.

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OBJECTIVES: The aim was to test whether or not soft tissue augmentation with a newly developed collagen matrix (CM) leads to volume gain in chronic ridge defects similar to those obtained by an autogenous subepithelial connective tissue graft (SCTG).

MATERIAL AND METHODS: In six dogs, soft tissue volume augmentation was performed by randomly allocating three treatment modalities to chronic ridge defects (CM, SCTG, sham-operated control). Impressions were taken before augmentation (baseline), at 28, and 84 days. The obtained casts were optically scanned and the images were digitally analysed. A defined region of interest was measured in all sites and the volume differences between the time points were calculated.

RESULTS: The mean volume differences per area between baseline and 28 days amounted to a gain of 1.6 mm (CM; SD+/-0.9), 1.5 mm (SCTG; +/-0.1), and a loss of 0.003 mm (control; +/-0.3). At 84 days, the mean volume differences per area to baseline measured a gain of 1.4 mm (CM; +/-1.1), 1.4 mm (SCTG; +/-0.4), and a loss of 0.3 mm (control; +/-0.3). The differences between CM and SCTG were statistically significant compared with control at 28 and 84 days (p<0.001).

CONCLUSION: Within the limits of this animal study, the CM may serve as a replacement for autogenous connective tissue.


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Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Center for Dental Medicine > Clinic for Preventive Dentistry, Periodontology and Cariology
04 Faculty of Medicine > Center for Dental Medicine > Clinic for Fixed and Removable Prosthodontics
Dewey Decimal Classification:610 Medicine & health
Deposited On:31 Jan 2011 09:37
Last Modified:05 Apr 2016 14:41
Publisher DOI:10.1111/j.1600-051X.2010.01581.x
PubMed ID:20642631

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