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Zanoni, R G; Bugnon, P; Deranleau, E; Nguyen, T M V; Brügger, D (2010). Walking the dog and moving the cat: rabies serology in the context of international pet travel schemes. Schweizer Archiv für Tierheilkunde, 152(12):561-568.

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Data of 13'469 blood samples from 10'999 dogs and 2'470 cats tested for rabies neutralizing antibodies within the framework of pet travel schemes were analysed for single and combined factors influencing antibody titres and failures. The time span between vaccination and drawing the blood sample was confirmed as a major source of failure in dogs with a proportion of 23 % at 4 months after primary vaccination (single dose). Failures in dogs and cats (titre < 0.5 IU) were significantly reduced after double primary vaccination (2 doses within 7 - 10 days), although failures reached comparable levels in dogs as early as 6 months after vaccination. In contrast, failure after vaccination was generally below 5 % in dogs and absent in cats after a booster applied at earliest 12 months after single primary vaccination. Statistically significant differences between the failures of the vaccine brands «Rabisin» (1.5 %), «Defensor» (6.7 %), «Nobivac Rabies» (11.0 %) and «Rabdomun» (18.2 %) were found in dogs but also between the titres induced in cats. Significant differences were found between different dog breeds with some small breeds showing a significantly higher responsiveness. Taken together, a new regimen for rabies vaccination consisting of double primary vaccination with a short interval of 7 - 10 days and a one-year booster appears to be highly recommended for dogs and cats.


4 citations in Web of Science®
4 citations in Scopus®
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Additional indexing

Other titles:Reisen mit Hunden und Katzen: Tollwutserologie im Zusammenhang mit internationalen Reisebestimmungen
Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Institute of Laboratory Animal Science
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Date:December 2010
Deposited On:10 Feb 2011 15:15
Last Modified:05 Apr 2016 14:45
Publisher:Hans Huber
Publisher DOI:10.1024/0036-7281/a000125
PubMed ID:21104630

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