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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-4537

Springer, B; Calligaris-Maibach, R C; Ritter, C; Böttger, E C (2008). TB drug resistance in a low endemic area 2004 to 2006: semi-quantitative drug susceptibility testing and genotyping. Journal of Clinical Microbiology, 46(12):4064-4067.



We determined quantitative levels and genetic mechanisms of resistance in drug resistant clinical isolates of Mycobacterium tuberculosis sampled over a period of three years (n = 45, 17 of which MDR). Our results lead us to hypothesize that some strains categorized by standard laboratory procedures of in vitro drug susceptibility testing as resistant to isoniazid, ethambutol or streptomycin may still respond to a treatment regimen including these agents.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Medical Microbiology
DDC:570 Life sciences; biology
610 Medicine & health
Date:December 2008
Deposited On:06 Nov 2008 13:06
Last Modified:28 Nov 2013 00:53
Publisher:American Society for Microbiology
Additional Information:Copyright: American Society for Microbiology
Publisher DOI:10.1128/JCM.01114-08
PubMed ID:18923010
Citations:Web of Science®. Times Cited: 8
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Scopus®. Citation Count: 9

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