Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-46294
Willoughby, C E; Ponzin, D; Ferrari, S; Lobo, A; Landau, K; Omidi, Y (2010). Anatomy and physiology of the human eye: effects of mucopolysaccharidoses disease on structure and function – a review. Clinical and Experimental Ophthalmology, 38(S1):2-11.
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The current paper provides an overview of current knowledge on the structure and function of the eye. It describes in depth the different parts of the eye that are involved in the ocular manifestations seen in the mucopolysaccharidoses (MPS). The MPS are a group of rare inheritable lysosomal storage disorders characterized by the accumulation of glycosaminoglycans (GAGs) in cells and tissues all over the body, leading to widespread tissue and organ dysfunction. GAGs also tend to accumulate in several tissues of the eye, leading to various ocular manifestations affecting both the anterior (cornea, conjunctiva) and the posterior parts (retina, sclera, optic nerve) of the eye.
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|Item Type:||Journal Article, refereed, further contribution|
|Communities & Collections:||04 Faculty of Medicine > University Hospital Zurich > Ophthalmology Clinic|
|DDC:||610 Medicine & health|
|Deposited On:||21 Feb 2011 10:08|
|Last Modified:||03 Dec 2013 05:54|
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