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Green, S M; Roback, M G; Krauss, B; Brown, L; McGlone, R G; Agrawal, D; McKee, M; Weiss, M; Pitetti, R D; Hostetler, M A; Wathen, J E; Treston, G; Garcia Pena, B M; Gerber, A C; Losek, J D; Oktay, C; Saetta, J P; Holloway, V; Heinz, P; Bleiberg, A H; Herd, D; Godambe, S A; Pershad, J; Luhmann, J D; Kennedy, R M; Dachs, R J; Priestley, S J; Acworth, J P (2010). Anticholinergics and ketamine sedation in children: a secondary analysis of atropine versus glycopyrrolate. Academic Emergency Medicine, 17(2):157-162.

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This secondary analysis unexpectedly found that the coadministered anticholinergic atropine exhibited a superior adverse event profile to glycopyrrolate during ketamine sedation. Any such advantage requires confirmation in a separate trial; however, our data cast doubt on the traditional premise that glycopyrrolate might be superior. Further, neither anticholinergic showed efficacy in decreasing airway and respiratory adverse events.


15 citations in Web of Science®
19 citations in Scopus®
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Additional indexing

Contributors:Emergency Department Ketamine Meta-analysis Study Group
Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Clinic for Surgery
Dewey Decimal Classification:610 Medicine & health
Deposited On:22 Feb 2011 09:09
Last Modified:05 Apr 2016 14:48
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:10.1111/j.1553-2712.2009.00634.x
PubMed ID:20370745

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