Green, S M; Roback, M G; Krauss, B; Brown, L; McGlone, R G; Agrawal, D; McKee, M; Weiss, M; Pitetti, R D; Hostetler, M A; Wathen, J E; Treston, G; Garcia Pena, B M; Gerber, A C; Losek, J D; Oktay, C; Saetta, J P; Holloway, V; Heinz, P; Bleiberg, A H; Herd, D; Godambe, S A; Pershad, J; Luhmann, J D; Kennedy, R M; Dachs, R J; Priestley, S J; Acworth, J P (2010). Anticholinergics and ketamine sedation in children: a secondary analysis of atropine versus glycopyrrolate. Academic Emergency Medicine, 17(2):157-162.
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This secondary analysis unexpectedly found that the coadministered anticholinergic atropine exhibited a superior adverse event profile to glycopyrrolate during ketamine sedation. Any such advantage requires confirmation in a separate trial; however, our data cast doubt on the traditional premise that glycopyrrolate might be superior. Further, neither anticholinergic showed efficacy in decreasing airway and respiratory adverse events.
|Contributors:||Emergency Department Ketamine Meta-analysis Study Group|
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > University Children's Hospital Zurich > Clinic for Surgery|
|DDC:||610 Medicine & health|
|Deposited On:||22 Feb 2011 10:09|
|Last Modified:||23 Nov 2012 15:12|
|Free access at:||Publisher DOI. An embargo period may apply.|
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