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Green, S M; Roback, M G; Krauss, B; Brown, L; McGlone, R G; Agrawal, D; McKee, M; Weiss, M; Pitetti, R D; Hostetler, M A; Wathen, J E; Treston, G; Garcia Pena, B M; Gerber, A C; Losek, J D; Oktay, C; Saetta, J P; Holloway, V; Heinz, P; Bleiberg, A H; Herd, D; Godambe, S A; Pershad, J; Luhmann, J D; Kennedy, R M; Dachs, R J; Priestley, S J; Acworth, J P (2010). Anticholinergics and ketamine sedation in children: a secondary analysis of atropine versus glycopyrrolate. Academic Emergency Medicine, 17(2):157-162.

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Abstract

This secondary analysis unexpectedly found that the coadministered anticholinergic atropine exhibited a superior adverse event profile to glycopyrrolate during ketamine sedation. Any such advantage requires confirmation in a separate trial; however, our data cast doubt on the traditional premise that glycopyrrolate might be superior. Further, neither anticholinergic showed efficacy in decreasing airway and respiratory adverse events.

Contributors:Emergency Department Ketamine Meta-analysis Study Group
Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Clinic for Surgery
DDC:610 Medicine & health
Language:English
Date:2010
Deposited On:22 Feb 2011 09:09
Last Modified:28 Nov 2013 00:36
Publisher:Wiley-Blackwell
ISSN:1069-6563
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:10.1111/j.1553-2712.2009.00634.x
PubMed ID:20370745
Citations:Web of Science®. Times Cited: 11
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Scopus®. Citation Count: 15

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