UZH-Logo

Maintenance Infos

Suppression of interleukin (IL)-8 and human beta defensin-2 secretion in LPS-and/or IL-1-Beta-stimulated airway epithelial A 549 cells by herbal formulation against respiratory infections (BNO 1030)


Hostanska, K; Melzer, J; Amon, A; Saller, R (2011). Suppression of interleukin (IL)-8 and human beta defensin-2 secretion in LPS-and/or IL-1-Beta-stimulated airway epithelial A 549 cells by herbal formulation against respiratory infections (BNO 1030). Journal of Ethnopharmacology, 134(2):228-233.

Abstract

BACKGROUND: Peritoneal dialysis (PD) catheter displacement is a major cause of dysfunction. Various catheter forms have been designed to improve outcome. One of them is based on the classical Tenckhoff catheter, but includes a small tungsten cylinder at the distal end to optimize location and to prevent dislocations. ♢

METHODS: In this retrospective study, we analyzed the functionality and complication profile of the self-locating catheter implanted at our center from November 2005 to September 2008 in our PD program. ♢

RESULTS: Data from 27 self-locating catheters implanted in 25 patients (12 women) were obtained. Patients were followed for up to 30 months (median observation time: 13 months), resulting in a cumulative study period of 357 PD months. A total of 22 complications were identified, including 1 episode of peritonitis per 52 patient-months, 1 tunnel infection, and 1 exit-site infection. The "functional catheter failure incidence rate" was approximately 0.01 catheters per month on PD (or approximately 1 catheter loss per 100 PD months). The catheter survival was 93% at 1 year. ♢

CONCLUSIONS: The "self-locating" PD catheter demonstrates low rates of catheter migration and dislocations, and good catheter survival.

BACKGROUND: Peritoneal dialysis (PD) catheter displacement is a major cause of dysfunction. Various catheter forms have been designed to improve outcome. One of them is based on the classical Tenckhoff catheter, but includes a small tungsten cylinder at the distal end to optimize location and to prevent dislocations. ♢

METHODS: In this retrospective study, we analyzed the functionality and complication profile of the self-locating catheter implanted at our center from November 2005 to September 2008 in our PD program. ♢

RESULTS: Data from 27 self-locating catheters implanted in 25 patients (12 women) were obtained. Patients were followed for up to 30 months (median observation time: 13 months), resulting in a cumulative study period of 357 PD months. A total of 22 complications were identified, including 1 episode of peritonitis per 52 patient-months, 1 tunnel infection, and 1 exit-site infection. The "functional catheter failure incidence rate" was approximately 0.01 catheters per month on PD (or approximately 1 catheter loss per 100 PD months). The catheter survival was 93% at 1 year. ♢

CONCLUSIONS: The "self-locating" PD catheter demonstrates low rates of catheter migration and dislocations, and good catheter survival.

Citations

5 citations in Web of Science®
6 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

6 downloads since deposited on 21 Feb 2011
0 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of Complementary Medicine
04 Faculty of Medicine > University Hospital Zurich > Clinic for Psychiatry and Psychotherapy
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2011
Deposited On:21 Feb 2011 17:51
Last Modified:05 Apr 2016 14:49
Publisher:Elsevier
ISSN:0378-8741
Publisher DOI:10.1016/j.jep.2010.12.006
PubMed ID:21167927
Permanent URL: http://doi.org/10.5167/uzh-46409

Download

[img]
Filetype: PDF - Registered users only
Size: 1MB
View at publisher

TrendTerms

TrendTerms displays relevant terms of the abstract of this publication and related documents on a map. The terms and their relations were extracted from ZORA using word statistics. Their timelines are taken from ZORA as well. The bubble size of a term is proportional to the number of documents where the term occurs. Red, orange, yellow and green colors are used for terms that occur in the current document; red indicates high interlinkedness of a term with other terms, orange, yellow and green decreasing interlinkedness. Blue is used for terms that have a relation with the terms in this document, but occur in other documents.
You can navigate and zoom the map. Mouse-hovering a term displays its timeline, clicking it yields the associated documents.

Author Collaborations