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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-46409

Hostanska, K; Melzer, J; Amon, A; Saller, R (2011). Suppression of interleukin (IL)-8 and human beta defensin-2 secretion in LPS-and/or IL-1-Beta-stimulated airway epithelial A 549 cells by herbal formulation against respiratory infections (BNO 1030). Journal of Ethnopharmacology, 134(2):228-233.

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BACKGROUND: Peritoneal dialysis (PD) catheter displacement is a major cause of dysfunction. Various catheter forms have been designed to improve outcome. One of them is based on the classical Tenckhoff catheter, but includes a small tungsten cylinder at the distal end to optimize location and to prevent dislocations. ♢

METHODS: In this retrospective study, we analyzed the functionality and complication profile of the self-locating catheter implanted at our center from November 2005 to September 2008 in our PD program. ♢

RESULTS: Data from 27 self-locating catheters implanted in 25 patients (12 women) were obtained. Patients were followed for up to 30 months (median observation time: 13 months), resulting in a cumulative study period of 357 PD months. A total of 22 complications were identified, including 1 episode of peritonitis per 52 patient-months, 1 tunnel infection, and 1 exit-site infection. The "functional catheter failure incidence rate" was approximately 0.01 catheters per month on PD (or approximately 1 catheter loss per 100 PD months). The catheter survival was 93% at 1 year. ♢

CONCLUSIONS: The "self-locating" PD catheter demonstrates low rates of catheter migration and dislocations, and good catheter survival.


5 citations in Web of Science®
6 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of Complementary Medicine
04 Faculty of Medicine > University Hospital Zurich > Clinic for Psychiatry and Psychotherapy
Dewey Decimal Classification:610 Medicine & health
Deposited On:21 Feb 2011 17:51
Last Modified:05 Apr 2016 14:49
Publisher DOI:10.1016/j.jep.2010.12.006
PubMed ID:21167927

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