Quick Search:

uzh logo
Browse by:
bullet
bullet
bullet
bullet

Zurich Open Repository and Archive

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-47333

Kuhbier, J W; Allmeling, C; Reimers, K; Hillmer, A; Kasper, C; Menger, B; Brandes, G; Guggenheim, M; Vogt, P M (2010). Interactions between spider silk and cells--NIH/3T3 fibroblasts seeded on miniature weaving frames. PLoS ONE, 5(8):e12032.

[img]
Preview
PDF
2MB

View at publisher

Abstract

Native spider silk does not require any modification to its application as a biomaterial that can rival any artificial material in terms of cell growth promoting properties. We could show adhesion mechanics on intracellular level. Additionally, proliferation kinetics were higher than in enzymatically digested controls, indicating that spider silk does not require modification. Recent findings concerning reduction of cell proliferation after exposure could not be met. As biotechnological production of the hierarchical composition of native spider silk fibres is still a challenge, our study has a pioneer role in researching cellular mechanics on native spider silk fibres.

Citations

9 citations in Web of Science®
11 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

87 downloads since deposited on 04 Mar 2011
46 downloads since 12 months

Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Division of Surgical Research
04 Faculty of Medicine > University Hospital Zurich > Clinic for Reconstructive Surgery
DDC:610 Medicine & health
Language:English
Date:9 August 2010
Deposited On:04 Mar 2011 08:17
Last Modified:12 Nov 2014 12:24
Publisher:Public Library of Science (PLoS)
ISSN:1932-6203
Publisher DOI:10.1371/journal.pone.0012032
PubMed ID:20711495

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page