Quick Search:

uzh logo
Browse by:
bullet
bullet
bullet
bullet

Zurich Open Repository and Archive 

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-47333

Kuhbier, J W; Allmeling, C; Reimers, K; Hillmer, A; Kasper, C; Menger, B; Brandes, G; Guggenheim, M; Vogt, P M (2010). Interactions between spider silk and cells--NIH/3T3 fibroblasts seeded on miniature weaving frames. PLoS ONE, 5(8):e12032.

[img]
Preview
PDF
2060Kb

Abstract

Native spider silk does not require any modification to its application as a biomaterial that can rival any artificial material in terms of cell growth promoting properties. We could show adhesion mechanics on intracellular level. Additionally, proliferation kinetics were higher than in enzymatically digested controls, indicating that spider silk does not require modification. Recent findings concerning reduction of cell proliferation after exposure could not be met. As biotechnological production of the hierarchical composition of native spider silk fibres is still a challenge, our study has a pioneer role in researching cellular mechanics on native spider silk fibres.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Division of Surgical Research
04 Faculty of Medicine > University Hospital Zurich > Clinic for Reconstructive Surgery
DDC:610 Medicine & health
Language:English
Date:09 August 2010
Deposited On:04 Mar 2011 09:17
Last Modified:03 Dec 2013 06:01
Publisher:Public Library of Science
ISSN:1932-6203
Publisher DOI:10.1371/journal.pone.0012032
PubMed ID:20711495
Citations:Web of Science®. Times Cited: 6
Google Scholar™

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page