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Rieder, F; Georgieva, M; Schirbel, A; Artinger, M; Zügner, A; Blank, M; Brenmoehl, J; Schölmerich, J; Rogler, G (2010). Prostaglandin E2 inhibits migration of colonic lamina propria fibroblasts. Inflammatory Bowel Diseases, 16(9):1505-1513.

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Abstract

PGE2 reduced the migration of CLPF via elevation of intracellular cAMP. Potential mechanisms are changes in expression of cytoskeletal proteins, failure of CLPF to polarize, and a decreased amount of pMLC. This might be a possible reason for the impairment of intestinal wound healing in IBD.

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11 citations in Web of Science®
13 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Gastroenterology and Hepatology
DDC:610 Medicine & health
Language:English
Date:2010
Deposited On:04 Mar 2011 08:21
Last Modified:27 Nov 2013 18:24
Publisher:Wiley-Blackwell
ISSN:1078-0998
Publisher DOI:10.1002/ibd.21255
PubMed ID:20803697

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