Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-47742
Kumar, N; Rehrauer, H; Cai, H; Baudis, M (2011). CDCOCA: A statistical method to define complexity dependence of co-occuring chromosomal aberrations. BMC Medical Genomics, 4(21):Online.
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Abstract
We have developed a method to detect associations of regional copy number abnormalities in cancer data. Along with finding statistically relevant CNA co-occurrences, our algorithm points towards a generally low specificity for co-occurrence of regional imbalances in CNA rich samples, which may have negative impact on pathway modeling approaches relying on frequent CNA events.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > Functional Genomics Center Zurich 07 Faculty of Science > Institute of Molecular Life Sciences |
| DDC: | 570 Life sciences; biology 610 Medicine & health |
| Language: | English |
| Date: | 03 March 2011 |
| Deposited On: | 24 Mar 2011 14:59 |
| Last Modified: | 23 Nov 2012 16:04 |
| Publisher: | BioMed Central |
| ISSN: | 1755-8794 |
| Publisher DOI: | 10.1186/1755-8794-4-21 |
| PubMed ID: | 21371302 |
| WoS Citation Count: | 0 |
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