Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-47742
Kumar, N; Rehrauer, H; Cai, H; Baudis, M (2011). CDCOCA: A statistical method to define complexity dependence of co-occuring chromosomal aberrations. BMC Medical Genomics, 4(21):Online.
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We have developed a method to detect associations of regional copy number abnormalities in cancer data. Along with finding statistically relevant CNA co-occurrences, our algorithm points towards a generally low specificity for co-occurrence of regional imbalances in CNA rich samples, which may have negative impact on pathway modeling approaches relying on frequent CNA events.
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|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > Functional Genomics Center Zurich
07 Faculty of Science > Institute of Molecular Life Sciences
|DDC:||570 Life sciences; biology
610 Medicine & health
|Date:||3 March 2011|
|Deposited On:||24 Mar 2011 13:59|
|Last Modified:||27 Nov 2013 20:50|
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