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What are origins and phylogeny of plant hemoglobins?


Vinogradov, S N; Hoogewijs, D; Arredondo-Peter, R (2011). What are origins and phylogeny of plant hemoglobins? Communicative & Integrative Biology, 4(4):42-58.

Abstract

Land plants and algae are now represented
by about 40 genomes. Although
most are incomplete, putative globins
appear to be present in all the ca. 30 land
plant genomes and in all except one algal
genomes. The globins have either the
canonical 3/3 α-helical fold characteristic
of vertebrate myoglobin (Mb) or 2/2
α-helical folds, characteristic of bacterial
globins with a truncated Mb-fold. In view
of the fairly complete picture of the globin
superfamily that is now available from
analyses of over 1,000 bacterial genomes
and >200 other eukaryote genomes, it is
now possible to seek answers to the following
twin questions: what is the phylogenetic
relationship of plant and algal
globins to those of other eukaryotes and
what is their likely bacterial origin? We
summarize below the available results.
Molecular phylogenetic analyses indicate
that plant and algal 3/3 globins are
related to bacterial flavohemoglobins and
vertebrate neuroglobins. Furthermore,
they also suggest that plant and algal 3/3
and group 1 2/2 Hbs originated from the
horizontal gene transfers that accompanied
the two generally accepted endosymbioses
of a proteobacterium and a
cyanobacterium with a eukaryote ancestor.
In contrast, the origin of the group 2
2/2 Hbs unexpectedly appears to involve
horizontal gene transfer from a bacterium
ancestral to Chloroflexi, Deinococcales,
Bacillli and Actinomycetes. We present
additional results which indicate that the
shared ancestry is likely to be with the
Chloroflexi alone.

Land plants and algae are now represented
by about 40 genomes. Although
most are incomplete, putative globins
appear to be present in all the ca. 30 land
plant genomes and in all except one algal
genomes. The globins have either the
canonical 3/3 α-helical fold characteristic
of vertebrate myoglobin (Mb) or 2/2
α-helical folds, characteristic of bacterial
globins with a truncated Mb-fold. In view
of the fairly complete picture of the globin
superfamily that is now available from
analyses of over 1,000 bacterial genomes
and >200 other eukaryote genomes, it is
now possible to seek answers to the following
twin questions: what is the phylogenetic
relationship of plant and algal
globins to those of other eukaryotes and
what is their likely bacterial origin? We
summarize below the available results.
Molecular phylogenetic analyses indicate
that plant and algal 3/3 globins are
related to bacterial flavohemoglobins and
vertebrate neuroglobins. Furthermore,
they also suggest that plant and algal 3/3
and group 1 2/2 Hbs originated from the
horizontal gene transfers that accompanied
the two generally accepted endosymbioses
of a proteobacterium and a
cyanobacterium with a eukaryote ancestor.
In contrast, the origin of the group 2
2/2 Hbs unexpectedly appears to involve
horizontal gene transfer from a bacterium
ancestral to Chloroflexi, Deinococcales,
Bacillli and Actinomycetes. We present
additional results which indicate that the
shared ancestry is likely to be with the
Chloroflexi alone.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > Institute of Physiology
07 Faculty of Science > Institute of Physiology

04 Faculty of Medicine > Center for Integrative Human Physiology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Language:English
Date:2011
Deposited On:02 May 2011 12:24
Last Modified:05 Apr 2016 14:54
Publisher:Landes Bioscience
ISSN:1942-0889
Free access at:Official URL. An embargo period may apply.
Official URL:http://www.landesbioscience.com/journals/27/article/15429/
Permanent URL: http://doi.org/10.5167/uzh-47957

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