Nebivolol exerts beneficial effects on endothelial function, early endothelial progenitor cells, myocardial neovascularization, and left ventricular dysfunction early after myocardial infarction beyond conventional β1-blockade

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-48654

Sorrentino, S A; Doerries, C; Manes, C; Speer, T; Dessy, C; Lobysheva, I; Mohmand, W; Akbar, R; Bahlmann, F; Besler, C; Schaefer, A; Hilfiker-Kleiner, D; Lüscher, T F; Balligand, J L; Drexler, H; Landmesser, U (2011). Nebivolol exerts beneficial effects on endothelial function, early endothelial progenitor cells, myocardial neovascularization, and left ventricular dysfunction early after myocardial infarction beyond conventional β1-blockade. Journal of the American College of Cardiology, 57(5):601-611.

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Abstract

Nebivolol improves LV dysfunction and survival early after MI likely beyond the effects provided by conventional β₁-receptor blockade. Nebivolol induced effects on NO-mediated endothelial function, early endothelial progenitor cells and inhibition of myocardial NADPH oxidase likely contribute to these beneficial effects of nebivolol early after MI.

Item Type:	Journal Article, refereed, original work
Communities & Collections:	04 Faculty of Medicine > Institute of Physiology 07 Faculty of Science > Institute of Physiology 04 Faculty of Medicine > Center for Integrative Human Physiology 04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiology
DDC:	570 Life sciences; biology 610 Medicine & health
Language:	English
Date:	2011
Deposited On:	14 Jul 2011 10:37
Last Modified:	23 Nov 2012 13:26
Publisher:	Elsevier
ISSN:	0735-1097
Publisher DOI:	10.1016/j.jacc.2010.09.037
PubMed ID:	21272752

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