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Nebivolol exerts beneficial effects on endothelial function, early endothelial progenitor cells, myocardial neovascularization, and left ventricular dysfunction early after myocardial infarction beyond conventional β1-blockade


Sorrentino, S A; Doerries, C; Manes, C; Speer, T; Dessy, C; Lobysheva, I; Mohmand, W; Akbar, R; Bahlmann, F; Besler, C; Schaefer, A; Hilfiker-Kleiner, D; Lüscher, T F; Balligand, J L; Drexler, H; Landmesser, U (2011). Nebivolol exerts beneficial effects on endothelial function, early endothelial progenitor cells, myocardial neovascularization, and left ventricular dysfunction early after myocardial infarction beyond conventional β1-blockade. Journal of the American College of Cardiology, 57(5):601-611.

Abstract

Nebivolol improves LV dysfunction and survival early after MI likely beyond the effects provided by conventional β₁-receptor blockade. Nebivolol induced effects on NO-mediated endothelial function, early endothelial progenitor cells and inhibition of myocardial NADPH oxidase likely contribute to these beneficial effects of nebivolol early after MI.

Nebivolol improves LV dysfunction and survival early after MI likely beyond the effects provided by conventional β₁-receptor blockade. Nebivolol induced effects on NO-mediated endothelial function, early endothelial progenitor cells and inhibition of myocardial NADPH oxidase likely contribute to these beneficial effects of nebivolol early after MI.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Physiology
07 Faculty of Science > Institute of Physiology

04 Faculty of Medicine > Center for Integrative Human Physiology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Language:English
Date:2011
Deposited On:14 Jul 2011 08:37
Last Modified:05 Apr 2016 14:57
Publisher:Elsevier
ISSN:0735-1097
Publisher DOI:10.1016/j.jacc.2010.09.037
PubMed ID:21272752
Permanent URL: http://doi.org/10.5167/uzh-48654

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