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Birch pollen-related food allergy: clinical aspects and the role of allergen-specific IgE and IgG4 antibodies


Geroldinger-Simic, M; Zelniker, T; Aberer, W; Ebner, C H; Eggers, C; Greiderer, A; Prem, N; Lidholm, J; Ballmer-Weber, B K; Vieths, S; Bohle, B (2011). Birch pollen-related food allergy: clinical aspects and the role of allergen-specific IgE and IgG4 antibodies. Journal of Allergy and Clinical Immunology, 127(3):616-622.e1.

Abstract

Birch pollen-related food allergy is highly prevalent and often perennial. High food allergen-specific IgG(4)/IgE ratios seem associated with food tolerance, potentially because specific IgG(4) blocks IgE binding to food allergens. Thus, the presence of food allergen-specific IgG(4) antibodies is no diagnostic marker for birch pollen-related food allergy.

Abstract

Birch pollen-related food allergy is highly prevalent and often perennial. High food allergen-specific IgG(4)/IgE ratios seem associated with food tolerance, potentially because specific IgG(4) blocks IgE binding to food allergens. Thus, the presence of food allergen-specific IgG(4) antibodies is no diagnostic marker for birch pollen-related food allergy.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Dermatology Clinic
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2011
Deposited On:04 Aug 2011 10:48
Last Modified:05 Apr 2016 14:58
Publisher:Elsevier
ISSN:0091-6749
Publisher DOI:https://doi.org/10.1016/j.jaci.2010.10.027
PubMed ID:21251701

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