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Parkinson's disease and the bones


Gnädinger, M; Mellinghoff, H U; Kaelin-Lang, A (2011). Parkinson's disease and the bones. Swiss Medical Weekly, 141:w13154.

Abstract

Any newly diagnosed patient with PD should be evaluated for the risk of falling and osteoporosis and routinely be supplemented with vitamin D. In the case of osteoporosis, blood samples for detecting underlying and treatable conditions should be taken and bisphosphonates administered to the patient. It is unclear whether drugs typically used for PD provoke or worsen osteoporosis. Nevertheless, every long-term medication should undergo safety studies to demonstrate lack of negative interference with bone metabolism. Drug admission authorities should demand these data when registering new substances or when renewing old admissions.

Any newly diagnosed patient with PD should be evaluated for the risk of falling and osteoporosis and routinely be supplemented with vitamin D. In the case of osteoporosis, blood samples for detecting underlying and treatable conditions should be taken and bisphosphonates administered to the patient. It is unclear whether drugs typically used for PD provoke or worsen osteoporosis. Nevertheless, every long-term medication should undergo safety studies to demonstrate lack of negative interference with bone metabolism. Drug admission authorities should demand these data when registering new substances or when renewing old admissions.

Citations

9 citations in Web of Science®
12 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of General Practice
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2011
Deposited On:22 Aug 2011 08:46
Last Modified:05 Apr 2016 14:58
Publisher:EMH Swiss Medical Publishers
ISSN:0036-7672
Publisher DOI:10.4414/smw.2011.13154
PubMed ID:21328097
Permanent URL: http://doi.org/10.5167/uzh-49179

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