Umbricht, D; Koller, R; Schmid, L; Skrabo, A; Grübel, C; Huber, T; Stassen, H (2003). How specific are deficits in mismatch negativity generation to schizophrenia? Biological Psychiatry, 53(12):1120-1131.
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Mismatch negativity deficits, and by extension deficits in early cortical auditory information processing, appear to be specific to schizophrenia. Animal and human studies implicate dysfunctional N-methyl-D-aspartate receptor functioning in MMN deficits. Thus MMN deficits may become a useful endophenotype to investigate the genetic underpinnings of schizophrenia, particularly with regard to the N-methyl-D-aspartate receptor.
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > Psychiatric University Hospital Zurich > Division of Psychiatric Research and Clinic for Psychogeriatric Medicine|
|DDC:||610 Medicine & health|
|Deposited On:||08 Sep 2011 11:26|
|Last Modified:||23 Nov 2012 14:01|
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