Quick Search:

uzh logo
Browse by:

Zurich Open Repository and Archive

Maintenance: Tuesday, July the 26th 2016, 07:00-10:00

ZORA's new graphical user interface will be relaunched (For further infos watch out slideshow ZORA: Neues Look & Feel). There will be short interrupts on ZORA Service between 07:00am and 10:00 am. Please be patient.

Mann, A; Thakur, G; Shukla, V; Ganguli, M (2008). Peptides in DNA delivery: current insights and future directions. Drug Discovery Today, 13(3-4):152-160.

Full text not available from this repository.

View at publisher


Peptides are emerging as attractive alternatives to cationic polymers and lipids for nonviral DNA delivery. Their remarkable properties such as efficient condensation of DNA, translocation across the cellular membrane, pH-sensitive membrane disruption, and efficient targeting of attached cargoes to the nucleus make them lucrative for researchers to explore their application in DNA delivery. In this review article, we focus on how the chemical nature, structural features and DNA complexation strategies of different peptides have been utilized for efficient DNA delivery. We also discuss their potential problems hindering in vivo application.


39 citations in Web of Science®
40 citations in Scopus®
Google Scholar™


Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > Psychiatric University Hospital Zurich > Division of Psychiatric Research and Clinic for Psychogeriatric Medicine
Dewey Decimal Classification:610 Medicine & health
Deposited On:13 Sep 2011 07:22
Last Modified:05 Apr 2016 15:00
Publisher DOI:10.1016/j.drudis.2007.11.008
PubMed ID:18275913

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page