Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-49631
Pascual-Marqui, R D; Lehmann, D; Koukkou, M; Kochi, K; Anderer, P; Saletu, B; Tanaka, H; Hirata, K; John, E R; Prichep, L; Biscay-Lirio, R; Kinoshita, T (2011). Assessing interactions in the brain with exact low-resolution electromagnetic tomography. Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences, 369(1952):3768-3784.
Scalp electric potentials (electroencephalogram; EEG) are contingent to the impressed current density unleashed by cortical pyramidal neurons undergoing post-synaptic processes. EEG neuroimaging consists of estimating the cortical current density from scalp recordings. We report a solution to this inverse problem that attains exact localization: exact low-resolution brain electromagnetic tomography (eLORETA). This non-invasive method yields high time-resolution intracranial signals that can be used for assessing functional dynamic connectivity in the brain, quantified by coherence and phase synchronization. However, these measures are non-physiologically high because of volume conduction and low spatial resolution. We present a new method to solve this problem by decomposing them into instantaneous and lagged components, with the lagged part having almost pure physiological origin.
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > Psychiatric University Hospital Zurich > Clinic for Affective Disorders and General Psychiatry Zurich East|
04 Faculty of Medicine > The KEY Institute for Brain-Mind Research
|DDC:||610 Medicine & health|
|Deposited On:||15 Sep 2011 09:00|
|Last Modified:||23 Nov 2012 15:04|
|Publisher:||Royal Society Publishing|
|Related URLs:||http://rsta.royalsocietypublishing.org/ (Publisher)|
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