Eich, D; Neuhaus, C; Gamma, A; Angst, J; Rossler, W; Ajdacic-Gross, V; Opravil, M (2007). Is depression a risk factor for heart complaints? Longitudinal aspects in the Zurich study. European Archives of Psychiatry and Clinical Neuroscience, 257(7):396-401.
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BACKGROUND: The objective of this longitudinal study was to assess the association between major depression and heart complaints in a population of young and healthy adults. METHODS: Starting at the age 20/21, participants of the Zurich Study underwent 6 structured, psychological interviews during a span of 20 years. We evaluated longitudinal data from 277 persons who participated in all 6 interviews including questions about heart complaints. RESULTS: Over 20 years, heart complaints were reported by two thirds of participants, and the frequency of depression was 11.4%. At the age of 40/ 41, heart complaints were significantly associated with earlier heart complaints and major depression, both more often in women. Recurrent brief depression showed a tendency, but neither minor depression nor depressive symptoms were predictive for later heart complaints. CONCLUSIONS: This study suggests that major depression is a predictor for heart complaints at the age of 40 and that the severity of depressive disorder in younger age has an effect on subsequent heart complaints. Follow-up data will help to elucidate whether these subjective heart complaints show any correlation with a later coronary heart disease.
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > Psychiatric University Hospital Zurich > Clinic for Psychiatry, Psychotherapy, and Psychosomatics|
04 Faculty of Medicine > Psychiatric University Hospital Zurich > Clinic for Clinical and Social Psychiatry Zurich West (former)
|DDC:||610 Medicine & health|
|Uncontrolled Keywords:||Depression/complications - Female - Heart Diseases/epidemiology/etiology - Humans - Interview, Psychological - Life Change Events - Longitudinal Studies - Male - Middle Aged - Questionnaires - Risk Factors - Switzerland/epidemiology|
|Deposited On:||28 Sep 2011 16:18|
|Last Modified:||28 Nov 2013 01:02|
|Citations:||Web of Science®. Times cited: 3|
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