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Modeling of chromosomal epigenetic silencing processes


Becskei, A; Scherrer, S; Kelemen, J Z; Murray, A E (2011). Modeling of chromosomal epigenetic silencing processes. Transcription, 2(4):173-178.

Abstract

Silenced genes in eukaryotes are packaged into heterochromatin. In addition to establishing a passive storage site for inactive genes in differentiated cells, silencing can play an active role in promoting cellular differentiation. Here, we describe quantitative modeling of silencing processes.

Silenced genes in eukaryotes are packaged into heterochromatin. In addition to establishing a passive storage site for inactive genes in differentiated cells, silencing can play an active role in promoting cellular differentiation. Here, we describe quantitative modeling of silencing processes.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:07 Faculty of Science > Institute of Molecular Life Sciences
Dewey Decimal Classification:570 Life sciences; biology
Language:English
Date:2011
Deposited On:18 Oct 2011 07:08
Last Modified:05 Apr 2016 15:01
Publisher:Landes Bioscience
ISSN:2154-1272
Publisher DOI:10.4161/trns.2.4.16344
PubMed ID:21922059
Permanent URL: http://doi.org/10.5167/uzh-49887

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