Quick Search:

uzh logo
Browse by:
bullet
bullet
bullet
bullet

Zurich Open Repository and Archive

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-5023

Wagner, C A (2008). When proton pumps go sour: Urinary acidification and kidney stones. Kidney International, 73(10):1103-1105.

[img]
Preview
Accepted Version
PDF
1MB

View at publisher

Abstract

H(+)-ATPases mediate urinary acidification along the collecting duct, and mutations in their B1 and a4 subunits result in distal renal tubular acidosis. The pathomechanisms by which these mutations affect pump activity are only poorly understood. Common polymorphisms may impair pump activity and may link the pump to a higher risk for alkaline urine and the development of kidney stones.

Citations

2 citations in Web of Science®
2 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

26 downloads since deposited on 14 Nov 2008
3 downloads since 12 months

Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > Center for Integrative Human Physiology
04 Faculty of Medicine > Institute of Physiology
07 Faculty of Science > Institute of Physiology
DDC:570 Life sciences; biology
610 Medicine & health
Language:English
Date:May 2008
Deposited On:14 Nov 2008 17:39
Last Modified:27 Nov 2013 20:41
Publisher:Nature Publishing Group
ISSN:0085-2538
Publisher DOI:10.1038/ki.2008.137
PubMed ID:18449176

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page